动物生理学教研室

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姓名: 李术

职称: 教授

系别: 基础兽医学

研究领域: 动物营养生理学与动物营养代谢病

办公电话:

电子邮箱: lishu@neau.edu.cn

个人简介
所获奖项
社会兼职
科研项目
讲授课程
论文著作
其他业绩

李术,三级教授,博士生导师,动物营养生理学团队负责人,民进黑龙江省委委员,黑龙江省第十二届、第十三届政协委员。中国畜牧兽医学会生理生化学会理事、动物毒物学分会理事等。Biol Trace Elem Res、Frontiers in Veterinary Science编委。

学习工作经历:

2007.09-至今,东北农业大学,动物医学学院,教授

2013.10-2014.10,美国德州农工大学,访问学者

2003.07-2007.08,东北农业大学,动物医学学院,副教授

2001.06-2003.07,中国农业大学,动物医学院,基础兽医学专业博士后

1998.09-2001.06 东北农业大学动物医学学院临床兽医学专业博士研究生

1992.09-1998.09,哈尔滨市综合牧场助理兽医师,兽医师

1987.09-1992.07 东北农学院兽医专业学生

获得黑龙江省科学技术奖(自然类)一等奖1项(第3名),黑龙江省科学技术奖(自然类)二等奖2项(第1名、第3名),黑龙江省高校科技将一等奖(第1名),黑龙江省畜牧科技奖一等奖1项(第3名)、二等奖1项(第2名)。代表性奖项如下:

1.禽硒缺乏症发病机理的研究,黑龙江省科学技术奖(自然类)一等奖,黑龙江省人民政府,第3名,2019.10.

2.常见环境内分泌干扰物对动物机体损伤机制的研究,黑龙江省科学技术奖(自然类)二等奖,黑龙江省人民政府,第1名,2021.12.

3.畜禽氟中毒机理及综合防治技术研究与推广应用,黑龙江省科学技术奖(科技进步类)二等奖,2006.08.

人才称号:

黑龙江省D类高层次人才

“东农学者计划”高层次人才(首席教授SX2)


中国畜牧兽医学会动物生理学与生物化学专业委员会理事

黑龙江省生理科学会第七届理事会理事


主持国家级、省部级和厅局级课题20余项,代表性项目如下:

1.抗阿维菌素单克隆抗体的研制,国家自然科学基金青年基金,2003.01-2003.12.

2.阿维菌素诱导鸽子神经细胞凋亡机理的研究,国家自然科学基金面上项目,2005.01-2007.12.

3. α-突触核蛋白在阿维菌素致鸽神经元细胞凋亡中的作用,国家自然科学基金面上项目,2010.01-2012.12.

4. microRNA-55在鸡缺硒性脾淋巴细胞凋亡中的作用机制研究,国家自然科学基金面上项目, 2015.01-2018.12.

5.基于硒蛋白调控中性粒细胞外捕网形成探讨鸡缺硒性动脉炎的发生机制,国家自然科学基金面上项目, 2019.01-2022.12.

6.低硒通过LncRNAWSF27-miRNA1696-GPX3轴调控细胞程序性坏死引起鸡肠炎的机制研究,国家自然科学基金面上项目, 2021.01- 2024.12.

7.基于RNA m6A甲基化调控细胞程序性坏死探讨缺硒鸡动脉损伤机制的研究,国家自然科学基金面上项目, 2024.01-2027.12.

8.硒蛋白在鸡缺硒性免疫功能障碍中作用机制的研究,黑龙江省自然科学基金重点项目,2022.07-2025.12.

9.环境有害气体因子对肉鸡免疫损伤的影响及机制,国家重点研发计划(子课题), 2016.7-2020.12.


本科生课程:动物生理学、动物生理学实验

硕士研究生课程:动物生理学与生物化学专题

博士研究生课程:系统生理学、动物生理学与生物化学研究进展、基础兽医学学科前沿专题讲座与研讨


发表SCI收录论文140余篇,ESI高被引19篇,热点论文1篇。2020年以来发表SCI收录论文如下:

2020年

1.Xin Chi, Guangliang Shi, Qing Zhang, Qingqing Liu, Hang Yin, Yiming Zhang, Shu Li (2020). Astilbin protects chicken peripheral blood lymphocytes from cadmium-induced necroptosis via oxidative stress and the PI3K/Akt pathway. Ecotoxicology and Environmental Safety, 190, 110064-110064. DOI: 10.1016/j.ecoenv.2019.110064. ISSN: 0147-6513

2.Xueyuan Hu,Siran Tan,Hang Yin,Pervez Ahmed Khoso,Zhe Xu, & Shu Li (2020). Selenium-mediated gga-miR-29a-3p regulates LMH cell proliferation, invasion, and migration by targeting COL4A2. Metallomics, 12 (3), 449-459. DOI: 10.1039/c9mt00266a. ISSN: 1756-5901

3.Jianqing Chen, Shuai Zhang, Jianyu Tong, Xiaojie Teng, Zhongyuan Zhang, Shu Li, Xiaohua Teng (2020). Whole transcriptome-based miRNA-mRNA network analysis revealed the mechanism of inflammation-immunosuppressive damage caused by cadmium in common carp spleens. Science of The Total Environment, 717, 137081-137081. DOI: 10.1016/j.scitotenv.2020.137081. ISSN: 0048-9697

4.Jiaxin Sun, Shengchen Wang, Yirong Cao, Shuting Wang, Shu Li (2020). Cadmium exposure induces apoptosis, inflammation and immunosuppression through CYPs activation and antioxidant dysfunction in common carp neutrophils. Fish & Shellfish Immunology, 99, 284-290. DOI: 10.1016/j.fsi.2020.02.015. ISSN: 1050-4648

5.Wei Wang, Qingqing Liu, Tianyi Zhang, Lu Chen, Shu Li, Shiwen Xu (2020). Glyphosate induces lymphocyte cell dysfunction and apoptosis via regulation of miR-203 targeting of PIK3R1 in common carp (Cyprinus carpio L.). Fish & Shellfish Immunology, 101, 51-57. DOI: 10.1016/j.fsi.2020.03.047. ISSN: 1050-4648

6.Qingqing Liu, Wei Wang, Yiming Zhang, Yuan Cui, Shiwen Xu, Shu Li (2020). Bisphenol A regulates cytochrome P450 1B1 through miR-27b-3p and induces carp lymphocyte oxidative stress leading to apoptosis. Fish & Shellfish Immunology, 102, 489-498. DOI: 10.1016/j.fsi.2020.05.009. ISSN: 1050-4648

7.Yiming Zhang, Qingqing Liu, Hang Yin, Yahong Min, Shu Li (2020). Selenium deficiency causes immune damage by activating the DUSP1/NF-κB pathway and endoplasmic reticulum stress in chicken spleen. Food & Function, 11 (7), 6467-6475. DOI: 10.1039/d0fo00394. ISSN: 2042-6496

8.Yiming Zhang, Qingqing Liu, Hang Yin, Shu Li (2020). Cadmium exposure induces pyroptosis of lymphocytes in carp pronephros and spleens by activating NLRP3. Ecotoxicology and Environmental Safety, 202, 110903-110903.DOI:10.1016/j.ecoenv.2020.110903.ISSN:0147-6513

9.Yuan Cui, Kai Yin, Yingying Zheng, Bing Wang, Yingying Qu, Shu Li, Hongjin Lin (2021). Mixed plasticizers aggravated apoptosis by NOD2-RIP2-NF-κB pathway in grass carp hepatocytes. Journal of Hazardous Materials, 402, 123527-123527. DOI: 10.1016/j.jhazmat.2020.123527. ISSN: 0304-3894

10.Fuqing Zhao, Jianping Qu, Wei Wang, Shu Li Shiwen Xu (2020). The imbalance of Th1/Th2 triggers an inflammatory response in chicken spleens after ammonia exposure. Poultry Science, 99 (8), 3817-3822. DOI: 10.1016/j.psj.2020.04.029. eISSN: 1525-3171

11.Linqian Qin, Yiming Zhang, Chunyan Wan, Zhu Wang,Yimei Cong, Shu Li (2020). MiR-196-5p involvement in selenium deficiency-induced immune damage via targeting of NFκBIA in the chicken trachea.. DOI: 10.1039/d0mt00164c. ISSN: 1756-5901

12.Zijiang Yang,bShengchen Wang, Kai Yin, Qiaojian Zhang, Shu Li (2020). MiR‐1696/GPx3 axis is involved in oxidative stress mediated neutrophil extracellular traps inhibition in chicken neutrophils. Journal of Cellular Physiology, 236 (5), 3688-3699. DOI: 10.1002/jcp.30105. ISSN: 0021-9541

13.Zhirong, Zhao, Qiaojian Zhang, Chunjing Xu, Shengchen Wang, Jiahe Li, Zhaoyi Liu, Shu Li (2020). Methionine selenium antagonizes LPS‐induced necroptosis in the chicken liver via the miR‐155/TRAF3/MAPK axis. Journal of Cellular Physiology, 236 (5), 4024-4035. DOI: 10.1002/jcp.30145. ISSN: 0021-9541

14.Qing Zhang,Kaixin Zhang,Yaling Han,Yiming Zhang,Xue Hou,Ling Zhou,Guangliang Shi, & Shu Li (2020). MicroRNA‐223 triggers inflammation in porcine aorta by activating NLRP3 inflammasome under selenium deficiency. Journal of Cellular Physiology, 236 (6), 4555-4564.DOI:10.1002/jcp.30178.ISSN:0021-9541

15.Yuan Cui, Xintong Zhang, Kai Yin, Xue Qi, Yue Zhang, Jinxi Zhang, Shu Li, Hongjin Lin (2021). Dibutyl phthalate-induced oxidative stress, inflammation and apoptosis in grass carp hepatocytes and the therapeutic use of taxifolin. Science of The Total Environment, 764, 142880-142880. DOI: 10.1016/j.scitotenv.2020.142880. ISSN: 0048-9697

16.Ming Li, Yiming Zhang, Shu Li (2020). Effects of selenium deficiency on testis development and autophagy in chicks. Italian Journal of Animal Science, 19 (1), 753-761. DOI: 10.1080/1828051x.2020. ISSN: 1594-4077

17.Qianru Chi, Xueyuan Hu, Bing Zhao, Qing Zhang, Kaixin Zhang, Shu Li (2021). Regulation of H2S-induced necroptosis and inflammation in broiler bursa of Fabricius by the miR-15b-5p/TGFBR3 axis and the involvement of oxidative stress in this process. Journal of Hazardous Materials, 406, 124682-124682. DOI: 10.1016/j.jhazmat.2020.124682. ISSN: 0304-3894

2021

18.Yiming Zhang, Hang Yin, Bing Shao, Xue Hua, Bo Huang, Honggui Liu, Shu Li (2021). Antagonistic effect of VDR/CREB1 pathway on cadmium-induced apoptosis in porcine spleen. Ecotoxicology and Environmental Safety, 209, 111819-111819.DOI:10.1016/j.ecoenv.2020.111819.ISSN:0147-6513

19.Zichan He, Linfei Jiao, Jinliang Wang, Zhiqiang Shen, Yingmei Cong, Shu Li (2021). MicroRNA-294 Regulates Apoptosis of the Porcine Cerebellum Caused by Selenium Deficiency via Targeting iNOS. Biological Trace Element Research, 199 (12), 4593-4603.DOI:10.1007/s12011-021-02583-8.ISSN:0163-4984

20.YimingLu,YanfeiHan, Hang Yin, Yingmei Cong, Guangliang Shi, Shu Li (2021). Cadmium induces apoptosis of pig lymph nodes by regulating the PI3K/AKT/HIF-1α pathway. Toxicology, 451, 152694-152694.DOI:10.1016/j.tox.2021.152694.ISSN:0300-483X

21.Jingying Ye, Xin Chi, Jinliang Wang, Zhiqiang Shen, Shu Li, Shiwen Xu (2021). High fat induces activation of the tryptophan-ERK-CREB pathway and promotes bone absorption in cage layers. Poultry Science, 100 (7), 101149-101149.DOI: 10.1016/j.psj.2021.101149. ISSN:0032-5791

22.Yiming Zhang, Zhaoyi Liu, Jing Lan, Jinliang Wang, Zhiqiang Shen ,Guangliang Shi, Shu Li (2021). Cadmium induces the thymus apoptosis of pigs through ROS-dependent PTEN/PI3K/AKT signaling pathway. Environmental Science and Pollution Research, 28 (29), 39982-39992.DOI:10.1007/s11356-021-13517-1.ISSN:0944-1344

23.Qianru Chi, Qing Zhang,YimingLu,Yiming Zhang, Shiwen Xu,Shu Li(2021). Roles of selenoprotein S in reactive oxygen species-dependent neutrophil extracellular trap formation induced by selenium-deficient arteritis. Redox Biology, 44, 102003-102003.DOI:10.1016/j.redox.2021.102003.ISSN:2213-2317

24.Nuan Song, Xiaojing Li, Yuan Cui, Tianyi Zhang, Shiwen Xu, Shu Li (2021). Hydrogen sulfide exposure induces pyroptosis in the trachea of broilers via the regulatory effect of circRNA-17828/miR-6631-5p/DUSP6 crosstalk on ROS production. Journal of Hazardous Materials, 418, 126172-126172.DOI:10.1016/j.jhazmat.2021.126172.ISSN:0304-3894

25.Xueyuan Hu, Qianru Chi, Zhaoyi Liu, Dayong Tao, Yu Wang, Yingmei Cong, Shu Li (2021). Transcriptome analysis reveals that hydrogen sulfide exposure suppresses cell proliferation and induces apoptosis through ciR-PTPN23/miR-15a/E2F3 signaling in broiler thymus. Environmental Pollution, 284, 117466-117466. DOI: 10.1016/j.envpol.2021.117466. ISSN: 0269-7491

26.Kaixin Zhang, Xuedie Gu, Jing Lan, Yiming Zhang, Pervez Ahmed Khoso, Zhaoyi Liu, Shu Li (2021). Selenium-deficient diet induces inflammatory response in the pig adrenal glands by activating TLR4/NF-κB pathway via miR-30d-R_1. Metallomics, 13 (7), 0-0. DOI: 10.1093/mtomcs/mfab037. ISSN: 1756-5901

27.Qianru Chi, Xueyuan Hu, Zhaoyi Liu, Yanfei Han, Dayong Tao, Shiwen Xu, Shu Li (2021). H2S exposure induces cell death in the broiler thymus via the ROS-initiated JNK/MST1/FOXO1 pathway. Ecotoxicology and Environmental Safety, 222, 112488-112488. DOI: 10.1016/j.ecoenv.2021.112488. ISSN: 0147-6513

28.Jianqing Chen, Bing Shao, Jinliang Wang, Zhiqiang Shen, Honggui Liu, Shu Li (2021). Chlorpyrifos caused necroptosis via MAPK/NF-κB/TNF-α pathway in common carp (Cyprinus carpio L.) gills. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, 249, 109126-109126.DOI:10.1016/j.cbpc.2021.109126.ISSN:1532-0456

29.Puyuan Xing, Yiming Zhang, Qianru Chi, Shu Li (2021). Zinc Alleviates Arsenic-Induced Inflammation and Apoptosis in the Head Kidney of Common Carp by Inhibiting Oxidative Stress and Endoplasmic Reticulum Stress. Biological Trace Element Research, 200 (5), 2380-2390.DOI:10.1007/s12011-021-02837-5.ISSN:0163-4984

2022年

30.Qing Zhang, Dongliu Luo, Xuedie Gu, Pervez Ahmed Khoso, Xiaodan Huang Shu Li (2022). MiR-144-3p targets STC1 to activate PI3K/AKT pathway to induce cell apoptosis and cell cycle arrest in selenium deficiency broilers. Journal of Inorganic Biochemistry, 226, 111665-111665.0. DOI: 1016/j.jinorgbio.2021.111665. ISSN: 0162-0134

31.Yu Wang, Yujiao He, Xueyuan Hu, Qianru Chi, Bing Zhao, Jingying Ye, Shu Li(2022). Regulating of LncRNA2264/miR-20b-5p/IL17RD axis on hydrogen sulfide exposure-induced inflammation in broiler thymus by activating MYD88/NF-κB pathway. Toxicology, 467, 153086-153086.DOI:10.1016/j.tox.2021.153086.ISSN:0300-483X

32.Shengchen Wang, Xia Zhao, Qingqing Liu, Yue Wang, Shu Li, Shiwen Xu (2022). Selenoprotein K protects skeletal muscle from damage and is required for satellite cells-mediated myogenic differentiation. Redox Biology, 50, 102255-102255. DOI: 10.1016/j.redox.2022.102255. ISSN: 2213-2317

33.Xuedie Gu,Yu Wang, Yujiao He, Bing Zhao, Qing Zhang, Shu Li (2022). MiR-1656 targets GPX4 to trigger pyroptosis in broilers kidney tissues by activating NLRP3 inflammasome under Se deficiency. The Journal of Nutritional Biochemistry, 105, 109001-109001. DOI: 10.1016/j.jnutbio.2022.109001. ISSN: 0955-2863

34.Qianru Chi, Tong Xu,Yujiao He, Zhe Li, Xinyu Tang, Fan Xue, Shu Li (2022). Polystyrene nanoparticle exposure supports ROS-NLRP3 axis-dependent DNA-NET to promote liver inflammation. Journal of Hazardous Materials, 439, 129502-129502. DOI: 10.1016/j.jhazmat.2022.129502. ISSN: 0304-3894

35.Xinyu Tang, Xue Fan, Tong Xu, Yujiao He, Qianru Chi, Zhe Li, Shu Li (2022). Polystyrene nanoplastics exacerbated lipopolysaccharide‐induced necroptosis and inflammation via the ROS/MAPK pathway in mice spleen. Environmental Toxicology, 37 (10), 2552-2565. DOI: 10.1002/tox.23618. ISSN: 1520-4081

36.Yujiao He, Zhe Li, Tong Xu, Dongliu Luo, Qianru Chi, Yiming Zhang, Shu Li (2022). Polystyrene nanoplastics deteriorate LPS-modulated duodenal permeability and inflammation in mice via ROS drived-NF-κB/NLRP3 pathway. Chemosphere, 307, 135662-135662. DOI: 10.1016/j.chemosphere.2022. ISSN: 0045-6535

37.Xiaojing Li, Xia Zhao, Yujie Yao, Mengyao Guo, Shu Li (2021). New insights into crosstalk between apoptosis and necroptosis co-induced by chlorothalonil and imidacloprid in Ctenopharyngodon idellus kidney cells. Science of The Total Environment, 780, 146591-146591. DOI: 10.1016/j.scitotenv.2021.146591. ISSN: 0048-9697

38.Lin Peng, Tong Xu, Xue Fan, Qianru Chi, Xinyu Tang, Zhe Li,Zhikun Bai, Shu Li (2022). Polystyrene nanoplastics exacerbate lipopolysaccharide-induced myocardial fibrosis and autophagy in mice via ROS/TGF-β1/Smad. Toxicology, 480, 153338-153338. DOI: 10.1016/j.tox.2022.153338. ISSN: 0300-483X

39.Yujiao He, Lin Peng, Xiaochun Zhao, Xue Fan, Xinyu Tang, Guangliang Shi, Shu Li (2022). Selenium Deficiency Induces Inflammatory Response and Decreased Antimicrobial Peptide Expression in Chicken Jejunum Through Oxidative Stress. Biological Trace Element Research, 201 (7), 3461-3473. DOI: 10.1007/s12011-022-03442-w. ISSN: 0163-4984

40.Kaixin Zhang, Xuedie Gu,Yu Xia, Xiaochun Zhao, Khoso Pervez Ahmed, Shu Li (2023). MiR-129-3p regulates ferroptosis in the liver of Selenium-deficient broilers by targeting SLC7A11. Poultry Science, 102 (1), 102271-102271.DOI:10.1016/j.psj.2022.102271.ISSN:0032-5791

41.Yujiao He, Xinyu Tang, Xue Fan, Zhe Li, Lin Peng, Guangliang Shi, Shu Li (2022). Selenium deficiency increased duodenal permeability and decreased expression of antimicrobial peptides by activating ROS/NF-κB signal pathway in chickens. BioMetals, 36 (1), 137-152. DOI: 10.1007/s10534-022-00468-4.ISSN: 0966-0844

2023年

42.Zhe Li, Tong Xu, Xue Fan, Kai Chen, Chunyan Wan, Xiang Li, Hang Yin, Shu Li (2023). Bisphenol A aggravate selenium deficiency‐induced apoptosis via miR‐215‐3p/Dio1 to activate ROS/PI3K/AKT pathway in chicken arterial. Journal of Cellular Physiology, 238 (6), 1256-1274. DOI: 10.1002/jcp.31007. ISSN: 0021-9541

43.Jiawen Cui, Minna Qiu, Yuhang Liu, Yuhao Liu, You Tang, Xiaohua Teng, Shu Li (2023). Nano-selenium protects grass carp hepatocytes against 4-tert-butylphenol-induced mitochondrial apoptosis and necroptosis via suppressing ROS-PARP1 axis. Fish & Shellfish Immunology, 135, 108682-108682. DOI: 10.1016/j.fsi.2023.108682. ISSN: 1050-4648

44.Yongzhen Du, Tong Xu, Dongliu Luo, Yixuan Wang, Hang Yin, Chengguo Liu, Shu Li (2023). Perfluorooctane sulfonate‐induced apoptosis in kidney cells by triggering the NOX4/ROS/JNK axis and antagonism of cannabidiol. Environmental Toxicology, 38 (7), 1651-1664. DOI: 10.1002/tox.23794. ISSN: 1520-4081

45.Xixi Wang, Tong Xu, Dongliu Luo,Shanshan Li, Xinyu Tang, Jiayi Ding, Hang Yin, Shu Li (2023). Cannabidiol Alleviates Perfluorooctanesulfonic Acid-Induced Cardiomyocyte Apoptosis by Maintaining Mitochondrial Dynamic Balance and Energy Metabolic Homeostasis. Journal of Agricultural and Food Chemistry, 71 (14), 5450-5462.DOI:10.1021/acs.jafc.2c08378.ISSN:0021-8561

46.Xue Fan, Yixuan Wang, Jintao Zhang, Hongjin Lin, Zhikun Bai, Shu Li (2023). Bisphenol A Regulates the TNFR1 Pathway and Excessive ROS Mediated by miR-26a-5p/ADAM17 Axis to Aggravate Selenium Deficiency-Induced Necroptosis in Broiler Veins. Biological Trace Element Research, DOI: 10.1007/s12011-023-03756-3. ISSN: 0163-4984

47.Yu Xia, Yiming Zhang, Jintao Zhang, Yongzhen Du, Yixuan Wang, Aiqiang Xu, Shu Li (2023). Cadmium exposure induces necroptosis of porcine spleen via ROS‐mediated activation of STAT1/RIPK3 signaling pathway. Environmental and Molecular Mutagenesis, 64 (7), 382-392. DOI: 10.1002/em.22565. ISSN: 0893-6692

48.Dongliu Luo, Jintao Zhang, Hang Yin, Shanshan Li, Shiwen Xu, Shu Li (2023). Cannabidiol alleviates perfluorooctane sulfonate-induced macrophage extracellular trap mediate inflammation and fibrosis in mice liver. Ecotoxicology and Environmental Safety, 263, 115374-115374. DOI: 10.1016/j.ecoenv.2023.115374. ISSN: 0147-6513

49.Yu Xia, Shanshan Li, Xixi Wang, Bing Zhao, Shasha Chen, Qihang Jiang, Shiwen Xu, Shu Li (2023). Astilbin targeted Sirt1 to inhibit acetylation of Nrf2 to alleviate grass carp hepatocyte apoptosis caused by PCB126-induced mitochondrial kinetic and metabolism dysfunctions. Fish & Shellfish Immunology, 141, 109000-109000.DOI:10.1016/j.fsi.2023.109000.ISSN:1050-4648

50.Dongliu Luo, Yiming Lu, Jintao Zhang, Xixi Wang, Yixuan Wang, Shiping Li, Shu Li (2023). The mechanism of acrolein exposure inhibited the release of neutrophil extracellular traps: By reducing respiratory burst and Raf/MEK/ERK pathway and promote cell apoptosis. Chemico-Biological Interactions, 385, 110744-110744.DOI:10.1016/j.cbi.2023.110744.ISSN:0009-2797

51.Jintao Zhang, Shanshan Li, YuXia, Dongliu Luo, Xixi Wang, Shiping Li, Shu Li (2023). Melatonin alleviates 3,3′,4,4′,5‐pentachlorobenzene induced colon injury by relieving oxidative stress. Environmental Toxicology, 38 (12), 2993-3005.DOI:10.1002/tox.23933.ISSN:1520-4081

52.Dongliu Luo, Yiming Lu, Qiaohan Liu, Hang Yin, Xiaodan Huang, Shu Li (2023). The mechanism of cadmium exposure-induced lymph node necroptosis and inflammation in piglets: Activation of CYP450 through VDR / CREB1 pathway. Research in Veterinary Science, 164, 105044-105044.DOI:10.1016/j.rvsc.2023.105044.ISSN:0034-5288

53.Peng Lin, Shasha Chen, Hongjin Lin, Chunyan Wan, Xiang Li, Shiwen Xu, Shu Li (2023). Bisphenol A exposure exacerbates tracheal inflammatory injury in selenium-deficient chickens by regulating the miR-155/TRAF3/ROS pathway. International Journal of Biological Macromolecules, 253, 127501-127501. DOI: 10.1016/j.ijbiomac.2023.127501. ISSN: 0141-8130

54.Shasha Chen, Tong Xu, Aiqiang Xu, Jiahong Chu, Dongliu Luo, Guangliang Shi, Shu Li (2023). Quercetin alleviates zearalenone-induced apoptosis and necroptosis of porcine renal epithelial cells by inhibiting CaSR/CaMKII signaling pathway. Food and Chemical Toxicology, 182, 114184-114184. DOI: 10.1016/j.fct.2023.114184. ISSN: 0278-6915

55.Dongliu Luo, Shasha Chen, Xixi Wang, Yixuan Wang, Pervez Ahmed Khoso, Shiwen Xu, Shu Li (2023). Unraveling the mechanism of quercetin alleviating perfluorooctane sulfonate-induced apoptosis in grass carp (Ctenopharyngodon idellus) hepatocytes: AMPK/mTOR-mediated mitophagy. Aquatic Toxicology, 265, 106769-106769. DOI: 10.1016/j.aquatox.2023.106769. ISSN: 0166-445X

2024年

56.Aiqiang Xu, Yixuan Wang, Dongliu Luo, Yu Xia, Hua Xue, Haidong Yao, Shu Li (2024). By regulating the IP3R/GRP75/VDAC1 complex to restore mitochondrial dynamic balance, selenomethionine reduces lipopolysaccharide‐induced neuronal apoptosis. Journal of Cellular Physiology, DOI: 10.1002/jcp.31190.ISSN:0021-9541

57.Dongliu Luo, Xinyu Tang, Yixuan Wang, Shuqi Ying, Yujiao He, Hongjin Lin, Pervez Ahmed Khoso, Shu Li (2024). Selenium deficiency exacerbated Bisphenol A-induced intestinal toxicity in chickens: Apoptosis and cell cycle arrest mediated by ROS/P53. Science of The Total Environment, 913, 169730-169730. DOI: 10.1016/j.scitotenv.2023.169730. ISSN: 0048-9697

58.Yu Xia, Dongliu Luo, Aiqiang Xu, Bing Zhao, Hongjin Lin, Haidong Yao, Shu Li (2024). Insight into the mechanism of melatonin in attenuating PCB126-induced liver injury: Resistance to ROS-dependent NETs formation to alleviate inflammation and lipid metabolism dysfunction. Ecotoxicology and Environmental Safety, 270, 115923-115923.DOI: 10.1016/j.ecoenv.2023.115923.ISSN:0147-6513

59.Shanshan Li, Yixuan Wang, Aiqiang Xu, Bing Zhao, Yu Xia, Yujiao He, Hua Xue, Shu Li (2024). Dietary selenomethionine reduced oxidative stress by resisting METTL3-mediated m6A methylation level of Nrf2 to ameliorate LPS-induced liver necroptosis in laying hens. The Journal of Nutritional Biochemistry, 109563-109563. DOI: 10.1016/j.jnutbio.2023.109563. ISSN: 0955-2863

60.Qianru Chi, Yu Xia, Dongliu Luo, Lixiu Zhu, Xiuqin Yang, Shu Li (2024). In vitro and in silico analyses reveal the toxicity of metolachlor to grass carp hepatocytes and the antagonism of melatonin. Pesticide biochemistry and physiology, 202, 105930. DOI: 10.1016/j.pestbp.2024.105930. ISSN: 0048-3575

61.Yongzhen Du, Yu Xia, Tong Xu, Haojie Hu, Yujiao He, Muyue Zhang, Shu Li (2024). Selenoprotein o as a regulator of macrophage metabolism in selenium deficiency-induced lung inflammation. International journal of biological macromolecules, 281(Pt 1), 136232. Advance online publication. DOI: 10.1016/j.ijbiomac.2024.136232. eISSN: 1879-0003

62.Yiming Zhang, Chunyu Wei, Jiayi Ding, Jiahong Chu, Bo Huang, Guangliang Shi, Shu Li (2024). Selenium deficiency modulates necroptosis-mediated intestinal inflammation in broiler through the lncRNAWSF27/miRNA1696/GPX3 axis. Journal of animal science, skae288. Advance online publication. DOI: 10.1093/jas/skae288. eISSN: 1525-3163

63.Xixi Wang, Jiayi Ding, Kai Chen, Haodong Hu, Bo Huang, Guangliang Shi, Shu Li,Probing Selenium-Deficient Chicken Spleen Th1/Th17 Differentiation Based on Selenoprotein W Targeting PKM2/HIF1α,Journal of Agricultural and Food Chemistry

获得授权专利4项,主编、副主编教材及专著7部。主持黑龙江省研究生课程思政案例1项、东北农业大学本科生“课程思政”示范课程1项、课程思政试点课程建设项目1项、东北农业大学校级一流本科课程(线下)1项、研究生课程思政高质量建设项目2项以及黑龙江省高等教育学会高等教育研究课题1项等。