马天文,博士,硕士生导师,中共党员。主要从事大动物肢蹄病及马病研究。发表文章30余篇,其中SCI论文10余篇。主持国家自然科学基金青年科学基金项目、新疆维吾尔自治区优秀博士后基金等科研项目。主讲《兽医外科学》和《小动物疾病学》本科课程。
1.主持国家自然科学基金青年项目,基于FGFR4-β-catenin途径探究齐墩果酸改善牛骨关节炎软骨ECM降解的作用机制,2025.01-2027.12;
2.主持新疆维吾尔自治区优秀博士后基金,促进创伤愈合水凝胶的制备及在马皮肤创伤修复中的应用研究,2025.01-2025.12;
1.Ma T, Ruan H, Lv L, et al.Oleanolic acid, a small-molecule natural product, inhibits ECM degeneration in osteoarthritis by regulating the Hippo/YAP and Wnt/β-catenin pathways.Food & function,2023,14(22), 9999–10013.
2.Ma T, Lv L, Yu Y, et al.Bilobalide Exerts Anti-Inflammatory Effects on Chondrocytes Through the AMPK/SIRT1/mTOR Pathway to Attenuate ACLT-Induced Post-Traumatic Osteoarthritis in Rats. Frontiers in pharmacology, 2022,13, 783506.
3.Ma T, Wen Y, Song X, et al.Puerarin inhibits the development of osteoarthritis through antiinflammatory and antimatrix-degrading pathways in osteoarthritis-induced rat model. Phytotherapy research,2021, 35(5), 2579-2593.
4.Ma T, Zhang Z, Song X, et al.Combined detection of COMP and CS846 biomarkers in experimental rat osteoarthritis: a potential approach for assessment and diagnosis of osteoarthritis. Journal of orthopaedic surgery and research, 2018,13(1), 230.
5.Ma T, Chen H, Ruan H, et al.Natural product, bilobalide, improves joint health in rabbits with osteoarthritis by anti-matrix degradation and antioxidant activities. Frontiers in veterinary science, 2022,9, 1034623.
6.Ma T, Jia L, Zhao J, et al.Ginkgolide C slows the progression of osteoarthritis by activating Nrf2/HO-1 and blocking the NF-κB pathway. Frontiers in pharmacology, 2022,13, 1027553.
7.Ma T, Li Y, Wang G, et al.Changes in Synovial Fluid Biomarkers after Experimental Equine Osteoarthritis. Journal of veterinary research, 2017, 61(4), 503–508.
8.马天文,于跃,吕良钰,等.白果内酯对IL-1β诱导的ATDC5软骨细胞自噬、增殖和凋亡的影响[J].畜牧兽医学报,2023,54(02):837-846.
9.马天文,王英雪,王明河,等.犬肠道淋巴管扩张症的临床诊治及预后分析[J].畜牧兽医学报,2023,54(07):3102-3107.
10.马天文,吕良钰,于跃,等.齐墩果酸抑制骨关节炎大鼠肌肉氧化损伤及软骨下骨异常骨重建[J].畜牧兽医学报,2022,53(11):4081-4088.