博士,教授,博士生导师,从事中兽医学的教学、科研及人才培养工作。在延边大学农学院攻读本科生和硕士研究生学位,东北农业大学动物医学学院攻读博士研究生学位。2002.12-2003.12,在日本东京农工大学访问学者。主要研究方向为中药防治畜禽疾病,目前已培养毕业的研究生69名。在国内、外期刊发表学术论文200余篇,出版书籍3部,授权的发明专利4项,软件著作权4项。目前,担任黑龙江省双一流课程“中兽医学实验”课程负责人,中兽医学科研团队负责人,东北农业大学中兽医研究所负责人,黑龙江省奶牛协同创新体系岗位专家。
兼任中国畜牧兽医学会中兽医学分会副理事长,黑龙江畜牧兽医学会副理事长,黑龙江省畜牧兽医学会中兽医学分会理事长,农业农村部新兽药注册咨询专家,中国兽医协会中兽医团体标准委员会副主任委员。
1.血竭素调控成纤维细胞增殖和胶原分泌促进创伤修复的机制研究,国家自然科学基金
(面上项目),批准号:31572561,起止时间:201601-201912。
2.香活性成分AKBA调控雪旺细胞促进周围神经损伤修复机制研究,国家自然科学基金
(面上项目),批准号:31972725,起止时间:202001-202312。
主讲本科生课程:《中兽医学》,《兽医针灸学》;
主讲研究生课程:《中药饲料添加剂(硕)》,《免疫中兽药学(博)》,《现代中兽药学临床诊断技术(博)》。
近5年以第1作者或通讯作者在国内外发表的代表性论文(英文为SCI收录,为中科院分区一、二区,中文为CSCD收录)
1.Tauroursodeoxycholic Acid Improves Nonalcoholic Fatty Liver Disease by Regulating Gut Microbiota and Bile Acid Metabolism,Journal of Agricultural and Food Chemistry,Accepted: August 19, 2024,This: https://doi.org/10.1021/acs.jafc.4c04630
2.Catalpol from Rehmannia glutinosa Targets Nrf2/NF-κB Signaling Pathway to Improve Renal Anemia and Fibrosis.American Journal of Chinese Medicine,2024,Vol. 52,1-35,DOI: 10.1142/S0192415X24500575.
3.Acetyl-11-keto-beta-boswellic acid modulates macrophagepolarization and Schwann cell migration to accelerate spinal cord injury repair in rats,CNS Neurosci Ther. 2024;30:e14642.
https://doi.org/10.1111/cns.14642
4.Acetyl-11-Keto-β-Boswellic Acid Accelerates the Repair of Spinal Cord Injury in Rats by Resisting Neuronal Pyroptosis with Nrf2,International Journal of Molecular Sciences,2024, 25, 358. https:// doi.org/10.3390/ijms25010358
5.LYC inhibits the AKT signaling pathway to activate autophagy and ameliorate TGFB-induced renal fibrosis.Autophagy,2024 May;20(5):1114-1133. doi: 10.1080/15548627.2023.2287930
6.Effect of Angelica Sinensis extract on the angiogenesis of preovulatory follicles (F1-F3) in late-phase laying hens,Poultry Science,2023 Feb;102(2):102415. doi: 10.1016/j.psj.2022.102415.
7.Ligusticum chuanxiong promotes the angiogenesis of preovulatory follicles(F1−F3) in late-phase laying hens,Poultry Science,2023 Mar;102(3):102430. doi: 10.1016/j.psj.2022.102430.
8.Lycopene attenuates the inflammation and apoptosis in aristolochic acid nephropathy by targeting the Nrf2 antioxidant system.Redox Biology,2022 Nov:57:102494. doi: 10.1016/j.redox.2022.102494,
9.Protective effects of maslinic acid on high fat diet-induced liver injury in mice.Life Sciences.2022 Jul 15:301:120634.doi: 10.1016/j.lfs.2022.120634.
10.Promotion effect of angelica sinensis extract on angiogenesis of chicken preovulatory follicles in vitro.Poultry Science,2022 Jul;101(7):101938.doi: 10.1016/j.psj.2022.101938.
11.Aqueous extract of Artemisia capillaris improves non-alcoholic fatty liver and obesity in mice induced by high-fat diet,Frontiers in Pharmacology,2022 Nov 28:13:1084435.doi: 10.3389/fphar.2022.1084435.
12.AKBA Promotes Axonal Regeneration Via RhoA/Rictor to Repair Damaged Sciatic Nerve,International Journal of Molecular Sciences,2022 Dec 14;23(24):15903. doi: 10.3390/ijms232415903.
13.Acetyl-11-keto-beta-boswellic acid promotes sciatic nerve repair after injury: molecular mechanism.Neural Regen Res,2022 Dec;17(12):2778-2784.doi: 10.4103/1673-5374.339494.
14.Acetyl-11-keto-β-boswellic acid regulates the repair of rat sciatic nerve injury by promoting the proliferation of Schwann cells.Life Sciences,2020 Aug 1:254:116887.doi: 10.1016/j.lfs.2019.116887.
15.外源性褪黑素对蛋鸡热应激的缓解作用,东北农业大学学报,2024,55(5)65-75.DOI:10.19720/j.cnki.issn.1005-9369.2024.05.007.
16.马兜铃酸Ⅰ对大鼠五脏的毒性及功能影响,中国畜牧兽医, 2022,49(7): 2757-2767,DOI:10.16431/j.cnki.1671-7236.2022.07.034.
17.生地黄与马兜铃配伍缓解马兜铃毒性的研究,中国畜牧兽医,2021,48(6): 2221-2229.DOI:10.16431/j.cnki.1671-7236.2020.09.032
18.基于抗菌及抗炎作用探究板蓝根微粉对雏鸡沙门菌病的防治效果,2021,41(12):2468-2496.DOI:10.19720/j.cnki.issn.1005-9369.2024.05.007.
19.愈创蓝油烃促进皮肤创伤修复的研究,中国兽医科学2021,51(11):1453-1461,DOI:10.16656/j.issn.1673-4696.2021.0178.
20.复方板蓝根口服液对雏鸡白痢沙门氏菌病的防治研究,云南农业大学学报(自然科学),2020,35(2):282−288,DOI: 10.12101/j.issn.1004-390X(n).201804029.
21.板蓝根微粉水提物抗大肠杆菌活性及其机制的探究,中国畜牧兽医,2020,47(9):2968-2978.DOI:10.16431/j.cnki.1671-7236.2020.09.032
22.板蓝根超微粉对大鼠免疫功能调节作用的研究,中国畜牧兽医,2019,46(7):2159-2166.DOI:10.16431/j.cnki.1671-7236.2019.07.034
23.复方诃子口服液抗犊牛大肠杆菌性腹泻的药理作用研究,中国畜牧兽医2019,46(1):305-312.DOI:10.16431/j.cnki.1671-7236.2019.01.036
24.复方中药缓解产蛋鸡热应激研究,东北农业大学学报,2022,53(2)27-35.DOI:10.19720/j.cnki.issn.1005-9369.2022.02.004.
出版专著:
1.生态养林蛙,中国农业出版社出版,ISBN:978-7-109-17205-0,2012.08,主编
2.hinese Veterinary Acupuncture and Moxibustion,中国农业出版社出版,ISBN:978-7-109-18541-8,2013.12,参编
3.犬的经穴与针灸图谱,湖北科学技术出版,湖北科学技术出版,ISBN:978-7-5352-9156-1,2018.12第3主编,
东北农业大学中兽医学科研团队共有8名成员,其中教授3人,副教授5人。团队负责人于文会,团队骨干姜晓文,马隽,石广亮,成员:葛铭,吕占军,闵亚宏,王海彬。团队主要研究方向:中药防治畜禽疾病。