刘艳艳,博士,副教授/硕导,动物药学教研室主任,主讲本科课程《药用植物学与生药学》、《中药炮制学》和《中药药物分析学》、研究生课程《分子生药学》和《中药药理学》,主要从事新型中兽药的研发及创制相关研究,主持黑龙江省教育科学规划项目一项、校级课程思政建设项目两项及农业农村部、黑龙江省重点研发计划子课题等科研项目多项,发表教学及科研论文20篇,参编出版中国农业部十三五规划教材一部,主编专著一部,校编教材两部,获得实用新型专利三项,参与并获得国家科学技术进步二等奖一项。
(1)中兽药质量标准的确定(810106),课题来源(农业农村部国家生猪产业技术体系子课题),27万,执行时间(如2017.9~2024,主持)
(2)黑龙江省科技厅,黑龙江省重点研发计划子课题, GA21B006-1,药食同源天然植物原料质量标准的研究, 2021-09至2024-08, 3万元,在研,主持
(3)北芪五加可溶性粉临床试验 (860053),横向课题,17.36万/21.7万,(2017.7-2017.11,主持)
(4)吡喹酮新型固体分散片的制备研究,东北农业大学地方常发病防治省高校重点实验室开放课题,1.5万(2012-2015,主持)
(5)铅中毒导致的鸡心脏毒性及硒的缓解作用,东北农业大学科研启动基金,6万(2012-2015,主持)
1.Xiaoyue Xiao, Yang Zhang , Kedi Sun , Shuoqi Liu , Qingmiao Li , Yu Zhang , Bello-Onaghise Godspower , Tong Xu , Zhiyun Zhang , Yanhua Li* , Yanyan Liu,*Enzymatic and ultrasound assistedβ-cyclodextrin extraction of active ingredients from Forsythia suspensa and their antioxidant and anti-inflammatory activities.UltrasonicsSonochemistry, 2024,8(108),106944.
2.Xuejiao Song, Chang Liu, Yang Zhang, Xiaoyue Xiao, Guorui Han, Kedi Sun, Shuoqi Liu, Zhiyun Zhang, Chunliu Dong, Yadan Zheng, Xueying Chen, Tong Xu, Yanyan Liu, Yanhua Li,Sustainable extraction of ligustilide and ferulic acid from Angelicae Sinensis Radix, for antioxidant and anti-inflammatory activities,Ultrasonics Sonochemistry,2023,94, 10634
3.韩国瑞,肖小玥,张阳,李艳华,陈雪英,王秀敏,秦俊杰,刘艳艳,基于网络药理学和分子对接探究归芪益母口服液治疗猪气虚血瘀证的作用机制[J].中国畜牧兽医, 2023, 50(02): 722-733.
4.王小榛,刘畅,宋雪娇,邢晨,唐阳,张岳峰,刘艳艳.基于网络药理学分析连翘治疗牛乳房炎的作用机制及体内验证.中国兽医学报2022,(12),2534-2542
5.Xiao-Zhen Wang , Xue-Jiao Song, Chang Liu , Chen Xing , Tong Wu 1, Yue Zhang , Jing Su , Jing-You Hao , Xue-Ying Chen, Zhi-Yun Zhang, Yan-Hua Li , Yan-Yan Liu,Active components and molecular mechanism of Syringa oblata Lindl. in the treatment of endometritis based on pharmacology network prediction,2022,(6)22:9:885952.
6.Tong Xu, Qiaohan Liu , Dan Chen, Yanyan Liu*,Atrazine exposure induces necroptosis through the P450/ROS pathway andcauses inflammation in the gill of common carp (Cyprinus carpio L.),Fish and Shellfish Immunology, 2022,(131)809–816
7.Liu Yan-Yan, Chen Xing-Ru., Wang Jin-Peng., Cui Wen-Qiang., Xing Xiao-Xu., Chen Xue-Ying., Ding Wen-Ya., God'spower Bello-Onaghise., Eliphaz Nsabimana., Sun Meng-Qing., Li Yan-Hua. Transcriptomic analysis reveals flavonoid biosynthesis of Syringa oblata Lindl. in response to different light intensity.BMC Plant Biology, 2019, 19(1).
8.Xing-RuChen,Yan-YanLiu,Yong-HuiZhou,Xiao-XuXing,Qian-WeiQu,Xue-YingChen,Wen-YaDing,Guang-LongCheng,Ai-JuanWei,Xi-WenFeng. Process optimization of syringa oblata lindl. by response surface methodology and its effect on staphylococcus xylosus biofilm. RSC Advance. 2019, 9(62), 36088-36096.
9.Liu Yan-Yan, Chen Xing-Ru., Gao Ling-Fei., Chen Mo., Cui Wen-Qiang., Ding Wen-Ya., Chen Xue-Ying., God'spower Bello-Onaghise., Li Yan-Hua. Syringa oblata Spectrum-Effect Relationships Between the Bioactive Ingredient of Lindl. Leaves and Its Role in Inhibiting the Biofilm Formation of Streptococcus suis. Frontiers in pharmacology, 2018, 9, 570.
10.Liu Yanyan, Wang Tianzi., Ding Wenya., Dong Chunliu., Wang Xiaoting., Chen Jianqing., Li Yanhua. Dissolution and oral bioavailability enhancement of praziquantel by solid dispersions. Drug Delivery & Translational Research, 2018, 8(3), 580-590.
11. Yanyan Liu, Xiaoyan Jiao,Xiaojie Teng, Xianhong Gu * and Xiaohua Teng * . Antagonistic effect of selenium on lead-induced inflammatory injury through inhibiting the nuclear factor-kB signaling pathway and stimulating selenoproteins in chicken hearts . RSC Adv. 2017,7, 24878 -24884.
12.刘艳艳,丁文雅,陈雪英,李艳华,李继昌,魏萍.动物药学兽医药剂学实践性教学环节的改革与初探[J].黑龙江畜牧兽医,2015(07):237-238.DOI:10.13881/j.cnki.hljxmsy.2015.0564.
13.刘艳艳,秦光,李继昌.PHA复方制剂对鸡体内NF-κB的调节作用研究[J].黑龙江畜牧兽医,2012,(15):125-128.DOI:10.13881/j.cnki.hljxmsy.2012.15.051.
14.刘艳艳,秦光,李继昌.PHA复方制剂对鸡新城疫疫苗的免疫增强作用[J].东北农业大学学报,2012,43(06):32-35.DOI:10.19720/j.cnki.issn.1005-9369.2012.06.007.
15.刘艳艳,秦光,李继昌.PHA复方制剂对鸡免疫功能及相关细胞因子的调节作用[J ]东北农业大学学报. 2011 (06)
16.刘艳艳,李继昌,陈雪英,丁文雅,王幸,徐强.蒲公英最佳药用部位、干燥温度及提取方法的初步考察[J]黑龙江畜牧兽医. 2010(19)
17.刘艳艳,尹光昕.黑龙江省蒲公英常见品种绿原酸与总黄酮的含量测定[J]中国民族民间医药. 2011(08)
18.刘艳艳,秦光,李继昌,金希文.冻融法提取植物血凝素的研究[J].黑龙江医药. 2011(03)
刘艳艳,秦光,李继昌.PHA复方制剂对鸡免疫功能及相关细胞因子的调节作用[J].东北农业大学学报. 2011(06)127
19.刘艳艳,秦光,李继昌.反胶束萃取植物血凝素前萃工艺研究[J].东北农业大学学报. 2011(05)
20.刘艳艳,盛尊来,李继昌.兽用药剂学的教学改革与探讨[J].东北农业大学学报(社会科学版),2007,(05):99-100.
刘艳艳所带领的中兽药提取团队,基于绿色、环保建立针对不同中兽药成分的提取方法,为新型中兽药的创制与开发奠定理论基础。